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EDITORIAL |
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Off-label use of drugs: An evil or a necessity?  |
p. 767 |
Vikram Gota, Jigeeshu V Divatia DOI:10.4103/0019-5049.171555 PMID:26903667 |
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SPECIAL ARTICLE |
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Does non-medical grade power cord compromise the safety of medical equipment? |
p. 769 |
V Padmavathi, PS Vishnu Prasad, Pankaj Kundra DOI:10.4103/0019-5049.171556 PMID:26903668A tertiary care 1000 bedded hospital contains more than 10,000 pieces of equipment worth approximately 41 million USD, while the power cords supplied along with the imported equipment do not comply with country-specific norms. Moreover, the local vendors procure power cords with type D/M plug to complete installation and also on-site electrical safety test is not performed. Hence, this project was undertaken to evaluate the electrical safety of all life-saving equipment purchased in the year 2013, referring to the guidelines of International Electrotechnical Commission 62353, the Association for the Advancement of Medical Instrumentation (AAMI) and National Fire Protection Association (NFPA)-99 hospital standard for the analysis of protective earth resistance and chassis leakage current. This study was done with a measuring device namely electrical safety analyser 612 model from Fluke Biomedical. |
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CLINICAL INVESTIGATIONS |
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A comparative study of effect of sevoflurane on intubating conditions with rocuronium in neurosurgical patients |
p. 774 |
Saikat Mitra, Shobha Purohit, Sonali Bhatia, Poonam Kalra, Satya Prakash Sharma DOI:10.4103/0019-5049.171557 PMID:26903669Background and Aims: Rocuronium may not always be the preferred relaxant for rapid sequence intubation. When 2% sevoflurane is used in conjunction with rocuronium, it may reduce the time required for achieving complete skeletal muscle relaxation with the intubating dose of rocuronium. Methods: This study was prospective, randomised, double-blind in nature and compared the effect of sevoflurane on intubation time and intubating conditions when used along with rocuronium. Thirty adult patients belonging to American Society of Anesthesiologists physical status Grades 1 and 2, of either gender aged between 30 and 65 years undergoing neurosurgical operations were randomly allocated into two equal groups: Group R received 0.8 mg/kg rocuronium, and Group RS received 0.8 mg/kg of rocuronium with 2% sevoflurane. Onset time of intubation was assessed using train-of-four stimuli. The intubating conditions were compared using the Cooper scoring system and the haemodynamic responses were compared between the two groups. Results: The onset time of intubation was 101.73 ± 10.28 s in Group R and 60.4 ± 4.1 s in Group RS (P < 0.001), with excellent intubating conditions in both groups and without any adverse effects. Significant differences in heart rate and mean arterial pressure were seen immediately after intubation, at 1 and 3 min (P < 0.05) between the two groups. Conclusion: Rocuronium 0.8 mg/kg along with 2% sevoflurane provides excellent intubating conditions within 60-66 s from its administration. |
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Does labour epidural slow the progress of labour and lead to complications? Obstetricians' perception working in private and public sector teaching hospitals in a developing country |
p. 779 |
Muhammad Sohaib, Samina Ismail DOI:10.4103/0019-5049.171559 PMID:26903670Background and Aims: Obstetricians play a major role in the decision making for provision of analgesia for the woman in labour. As epidural analgesia (EA) is the most preferred technique, it is important to know obstetricians' perception regarding its effect on progress of labour and associated complications. Methods: The 6 months cross-sectional study included 114 obstetricians from teaching hospitals. After informed consent, obstetricians were asked to fill a predesigned questionnaire containing 13 close ended questions regarding their perception on the effect of EA on progress of labour, EA complications and whether they would recommend EA to their patients or not. Other variables included age, gender, training in EA, practice type and hospital settings (private or public sector). Results: Majority of the obstetricians had the perception of EA prolonging the first stage (89.5%) and second stage (98.2%) of labour, increasing the rate of caesarean section (87.7%), instrumental delivery (58.8%) and increasing the incidence of backache (85.5%). None of the obstetricians received any formal training in EA. Majority (84.2%) were not sure if they would recommend EA to their patients. When these responses were compared between public and private sector, a statistically higher percentage (P < 0.001) of public sector obstetricians had negative perception of EA. Conclusion: Perception of obstetrician regarding EA is contrary to the current evidence. There is a need to introduce formal curriculum on EA in obstetric training program and conduct regular refresher courses. |
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Comparison between intravenous dexmedetomidine and local lignocaine infiltration to attenuate the haemodynamic response to skull pin head holder application during craniotomy |
p. 785 |
Anu Paul, Handattu Mahabaleswara Krishna DOI:10.4103/0019-5049.171558 PMID:26903671Background and Aims: Skull pin application is intensely painful and can be accompanied by detrimental haemodynamic changes. We compared intravenous (IV) dexmedetomidine with local infiltration of lignocaine at pin application sites to attenuate haemodynamic changes associated with pin application. Methods: Fifty-two patients undergoing craniotomy were randomised to either group dexmedetomidine (received 1 μg/kg dexmedetomidine over 10 min starting at induction of anaesthesia) or group lignocaine (received 3 ml of 2% lignocaine infiltration at pin application sites before pin application). Anaesthetic protocol was standardised. Heart rate (HR) and mean arterial pressure (MAP) were recorded at the following time intervals, pre-induction baseline, pre-infiltration, post-infiltration, pre-pin application and post-pin application at 1, 2, 3, 4, 5, 10 and 15 min. Statistical analysis was done using independent samples t-test, Fisher exact test and Chi-square test. Results: HR and MAP were comparable between the groups at all the study intervals. The incidence of adverse haemodynamic effects attributable to pin application (tachycardia and/or hypertension) was comparable between the groups (2 patients in group dexmedetomidine and 5 in group lignocaine). However, the incidence of hypotension and/or bradycardia was significantly greater in the dexmedetomidine group (19 patients in group dexmedetomidine and 5 patients in group lignocaine; P = 0.0007). Conclusion: IV dexmedetomidine 1 mcg/kg over 10 min is comparable to local infiltration of 2% lignocaine at pin application sites to attenuate the haemodynamic response associated with skull pin application. However, use of dexmedetomidine is associated with significantly higher incidence of hypotension and bradycardia. |
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Incident reporting in post-operative patients managed by acute pain service |
p. 789 |
Syeda Fauzia Hasan, Mohammad Hamid DOI:10.4103/0019-5049.171561 PMID:26903672Background and Aims: Incident reporting is a reliable and inexpensive tool used in anaesthesia to identify errors in patient management. A hospital incident reporting system was already present in our hospital, but we were unable to find any incident related to acute pain management. Hence, acute pain service (APS) was started for voluntary incident reporting in post-operative patients to identify critical incidents, review the root cause and suggest remedial measures. Methods: All post-operative patients managed by APS were included in this observational study. A proforma was developed by APS, which included information about the type of incident (equipment and patient-related, human errors), severity of incident, person responsible and suggestions to prevent the same incident in the future. Patients and medical staff were informed about the reporting system. Whenever an incident was identified, a proforma was filled out by APS resident and data entered in SPSS programme. Results: Total of 98 (1.80%) incidents were reported in 5432 patients managed by APS during 3 years period. Average age of the patients was 46 ± 17 years. Majority of incidents were related to epidural care (71%) and occurred in surgical wards (87%). Most of the incidents occurred due to human error and infusion delivery set-related defects. Conclusion: Incident reporting proved to be a feasible method of improving quality care in developing countries. It not only provides valuable information about areas which needed improvement, but also helped in developing strategies to improve care. Knowledge and attitudes of medical and paramedical staff are identified as the targeted area for improvement. |
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Current views and practice of faculty members and consultants regarding 'Publications in India': A cross-sectional study |
p. 794 |
Madhuri S Kurdi, Ashwini Halebid Ramaswamy, Laxmikant Lokare, Jagadish G Sutagatti DOI:10.4103/0019-5049.171567 PMID:26903673Background and Aims: There is an increasing enthusiasm and pressure to submit scientific articles to journals for publication due to official policies. This has led to increased stress on authors and editors and in issues like plagiarism. We planned a cross-sectional study with an aim to explore the current publication related views and practice of faculty members and consultants. Methods: We conducted a questionnaire based prospective survey with 22 questions divided into parts. Print and electronic versions were sent to around 18,270 members in total, a majority of whom were anaesthesiologists and 600 members responded to our questionnaire. A database was created and analysed using Microsoft Excel. Results: About 80% felt that online journals were better read than print journals. Eighty eight percent agreed that publications improve academic skills. The Medical Council of India requirements to publish in reputed journals were cited as the main reasons for plagiarism. The publication rule had become a burden for 46% respondents. Review articles were most likely to be read though clinical investigations were considered to be of maximum academic significance. Review/publishing time followed by author requirements and journal indexing were the points our respondents liked to see most when choosing a journal for article submission. Conclusion: Our survey results depict the current author related views and trends in publication practice which may guide in evidence-based policy making. |
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EVIDENCE BASED DATA |
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Current practice of difficult airway management: A survey  |
p. 801 |
MC Rajesh, K Suvarna, S Indu, Taznim Mohammed, A Krishnadas, Priyanka Pavithran DOI:10.4103/0019-5049.171571 PMID:26903674Background and Aims: Difficult airway (DA) management depends on both training and actual usage of the various approaches in the event of difficulty. The aim of the study was to assess how well the anaesthesiologists are equipped to deal with DA situations. The current practice preference of DA management was also assessed. Methods: A questionnaire was distributed in a continuing medical education (CME) programme dedicated to DA and responses were noted and analysed, using Statistical Package for Social Sciences (SPSS) version 18. Results: The response rate was 73%. Airway assessment was performed by majority. Sixty eight percent consultants and 47% residents were well aware of the American Society of Anesthesiologists' DA algorithm. 67% consultants and 65% residents attended at least one CME on DA in the previous 5 years. There was an overall deficiency of video laryngoscopes, retrograde intubation and cricothyrotomy sets. Most of the respondents were comfortable in using supraglottic airway devices (SGADs). In anticipated DA, the preferred choice of management for junior doctors was attempting conventional method once and awake fibreoptic bronchoscopy (FOB) for the experienced. In unanticipated DA, most of the residents and consultants opted for SGAD. Extubation strategy was similar for both. Thirty four percent of respondents experienced a 'cannot intubate-cannot ventilate' situation at least once. Conclusion: Our survey showed that most respondents performed routine pre-operative airway assessment. A good armamentarium of airway gadgets should be made available in hospitals. Further training in techniques like video laryngoscopy, FOB or cricothyrotomy are essential. |
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CASE REPORTS |
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Anaesthetic management of extra-pleural pneumonectomy and hyperthermic intrathoracic chemotherapy procedure |
p. 807 |
Jalaja Koppa Ramegowda, Mohammed Abdul Salam, Vasant Nayak, Shabber Zaveri DOI:10.4103/0019-5049.171574 PMID:26903675Malignant pleural mesothelioma is a rare tumour with survival of 9-17 months after diagnosis. Radical surgical resection by extra-pleural pneumonectomy combined with hyperthermic intrathoracic chemotherapy has shown to improve patient survival and better microscopic tumour control. Anaesthetic management of this procedure is challenging due to the complex pathophysiological changes associated with prolonged duration of surgery, one- lung ventilation, haemodynamic instability due to major blood loss, temperature variations including heat loss during pneumonectomy and rapid rise in temperature during hyperthermic chemotherapy, cardiac arrhythmias due to exposure to heated chemotherapeutics, cisplatin toxicity and acid-base changes. Intra-operative management involves protective ventilation, regulation of temperature and haemodynamics along with prevention of complications associated with 'heated chemotherapeutics'. Thorough pre-operative assessment and preparation, advanced intra-operative monitoring with prompt corrective interventions, will help in improved patient outcome in the immediate post-operative period. We present one such case done for the 1 st time in India. |
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Perioperative management of patient with Bombay blood group undergoing mitral valve replacement |
p. 811 |
Shio Priye, J Sathyanarayan, S Shivaprakash, Durgaprasad Reddy DOI:10.4103/0019-5049.171577 PMID:26903676Bombay red blood cell phenotype is an extremely rare blood type for which patients can receive only autologous or Bombay phenotype red blood cells. We report a case of stenotic mitral valve with Bombay phenotype who underwent minimal invasive right lateral thoracotomy for the replacement of the mitral valve. A male patient from Bangladesh presented to the hospital with New York Heart Association III symptoms. His medical evaluation revealed severe mitral valve stenosis and mild aortic valve regurgitation. The patient received erythropoietin, intravenous iron succinate and folic acid tablets. Autologous blood transfusion was carried out. The mitral valve was replaced with a prosthetic valve successfully. After weaning off from cardiopulmonary bypass, heparinisation was corrected with protamine. Post-operatively, the patient received autologous red blood cells. The patient recovered after 1-day of inotropic support with adrenaline and milrinone, and diuretics and was discharged on the 5 th post-operative day. |
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BRIEF COMMUNICATIONS |
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Peripherally inserted central venous catheter line removal leading to brachial vein stripping- Need for more caution |
p. 814 |
Aarti Kabra, Atul Purohit, Vinod Parashar DOI:10.4103/0019-5049.171580 PMID:26903677 |
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Perioperative anaesthetic management of phaeochromocytoma associated with uncorrected tetralogy of Fallot |
p. 816 |
Chinmayi S Patkar, Namita Baldwa, Sona Dave, Pinakin Gujjar DOI:10.4103/0019-5049.171591 PMID:26903678 |
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LETTERS TO EDITOR |
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Anaesthetic management of bilateral hand transplantation |
p. 819 |
Sunil Rajan, Ramanathan Kannan Suppiah, Jerry Paul, Lakshmi Kumar DOI:10.4103/0019-5049.171593 PMID:26903679 |
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Thoracic spinal cord stimulation for low back pain in a patient with permanent pacemaker |
p. 820 |
Dimitrios Vassilakos, Barbara Fyntanidou, Vasilios Grosomanidis, Al-Kaisy Adnan DOI:10.4103/0019-5049.171596 PMID:26903680 |
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Ultrasound guided brachial block in a case of brachial plexus hypertrophy |
p. 822 |
John George Karippacheril, Shetty Nanda DOI:10.4103/0019-5049.171597 PMID:26903681 |
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A simple test of baricity for subarachnoid drugs |
p. 823 |
Jyoti Sharma, Ajay Kumar Goila, Rajesh Sood DOI:10.4103/0019-5049.171599 PMID:26903682 |
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Spurious oxygen saturation value: A dilemma for anaesthesiologist |
p. 826 |
Amit Goyal, Himanshu Khurana, Sangeeta Khanna, Yatin Mehta DOI:10.4103/0019-5049.171601 PMID:26903683 |
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Gum elastic bougie as a tube exchanger: Modified technique |
p. 827 |
Goneppanavar Umesh, KS Sushma, M Sindhupriya, UN Swarnamba DOI:10.4103/0019-5049.171604 PMID:26903684 |
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Insulin IP Calc: A smartphone application for insulin infusion protocol in Intensive Care Units |
p. 829 |
John George Karippacheril, Rashmi Teresa Mathai, Sona Susan Abraham DOI:10.4103/0019-5049.171607 PMID:26903685 |
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COMMENTS ON PUBLISHED ARTICLE |
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Aluminium phosphide poisoning: Need for revised treatment guidelines |
p. 831 |
Subramanian Senthilkumaran, Chidambaram Ananth, Ritesh G Menezes, Ponniah Thirumalaikolundusubramanian DOI:10.4103/0019-5049.171624 PMID:26903686 |
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