Indian Journal of Anaesthesia

CASE SERIES
Year
: 2021  |  Volume : 65  |  Issue : 4  |  Page : 331--335

Anaesthetic implications and transfusion practices in ABO incompatible living donor liver transplantation: Case series


Sindhu Balakrishnan1, Lakshmi Kumar1, Divya Daniel1, Sudhindran Surendran2 
1 Department of Anaesthesiology and Critical Care, Amrita Institute of Medical Sciences, Amrita Vidya Vishwapeetham, Kochi, Kerala, India
2 Department of Gastrosurgery and Solid Organ Transplant, Amrita Institute of Medical Sciences, Amrita Vidya Vishwapeetham, Kochi, Kerala, India

Correspondence Address:
Lakshmi Kumar
Department of Anaesthesia and Critical Care, Amrita Institute of Medical Sciences, Amrita Vidya Viswapeetham, Kochi - 682 021, Kerala
India

ABO incompatible liver transplants (ABOi LT) are considered as a life-saving option when compatible donor grafts are unavailable. Fourteen adults (right lobe graft) and three children (left lateral segment/lobe) who underwent ABOi LT from living donors between 2011 and 20 period were analysed for transfusions and desensitisation protocols. All recipients received packed red blood cells (PRBC) of their own group. AB plasma that does not contain any antibody was transfused in eight patients and donor group plasma in others. None of the patients developed transfusion related complications. Plasmapheresis and rituximab/bortezumab desensitisation was practised in 11 patients, only rituximab in four, only plasmapheresis in one, and no treatment in a 1 year child. Rejection was manifest in three patients while nine patients developed infections and sepsis. A working knowledge of the blood and product transfusions in ABOi LT is crucial for the anaesthesiologist. Perioperative management and impact of desensitisation protocol are discussed.


How to cite this article:
Balakrishnan S, Kumar L, Daniel D, Surendran S. Anaesthetic implications and transfusion practices in ABO incompatible living donor liver transplantation: Case series.Indian J Anaesth 2021;65:331-335


How to cite this URL:
Balakrishnan S, Kumar L, Daniel D, Surendran S. Anaesthetic implications and transfusion practices in ABO incompatible living donor liver transplantation: Case series. Indian J Anaesth [serial online] 2021 [cited 2021 Jul 29 ];65:331-335
Available from: https://www.ijaweb.org/article.asp?issn=0019-5049;year=2021;volume=65;issue=4;spage=331;epage=335;aulast=Balakrishnan;type=0