Indian Journal of Anaesthesia

REVIEW ARTICLE
Year
: 2020  |  Volume : 64  |  Issue : 10  |  Page : 835--841

Hyperbaric oxygen therapy: Can it be a novel supportive therapy in COVID-19?


Kirubanand Senniappan1, Salome Jeyabalan1, Pradeep Rangappa2, Muralidhar Kanchi3 
1 Department of Anaesthesia, Narayana Institute of Cardiac Sciences, Narayana Health, Bangalore, Karnataka, India
2 Department of Intensive Care, Columbia Asia Hospitals, Bangalore, Karnataka, India
3 Department of Anaesthesia and Intensive Care, Narayana Institute of Cardiac Sciences, Narayana Health, Bangalore, Karnataka, India

Correspondence Address:
Muralidhar Kanchi
Department of Anaesthesia and Intensive Care, Narayana Hrudayalaya, #258/A, Bommasandra Industrial Area, Anekal Taluk, Bangalore, Karnataka - 560 099
India

The coronavirus disease 2019 (COVID-19) is a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV2). Although 85% of infected patients remain asymptomatic, 5% show severe symptoms such as hypoxaemic respiratory failure and multiple end organ dysfunction (MODS) requiring intensive care unit (ICU) admission with a mortality rate of about 2.8%. Since a definitive treatment is yet to be identified, preventive and supportive strategies remain the mainstay of management. Supportive measures such as oxygen therapy with nasal cannula, face mask, noninvasive ventilation, mechanical ventilation and even extreme measures such as extracorporeal membrane oxygenation (ECMO) fail to improve oxygenation in some patients. Hence, hyperbaric oxygen therapy (HBOT) has been proposed as a supportive strategy to improve oxygenation in COVID-19 patients. HBOT is known to increase tissue oxygenation by increasing the amount of dissolved oxygen in plasma. HBOT also mitigates tissue inflammation thus reducing the ill effects of cytokine storm in COVID-19 patients. Though there is limited literature available on HBOT in COVID-19 patients, considering the present need for additional supportive therapy to improve oxygenation, HBOT has been proposed as a novel supportive treatment in COVID-19 patients.


How to cite this article:
Senniappan K, Jeyabalan S, Rangappa P, Kanchi M. Hyperbaric oxygen therapy: Can it be a novel supportive therapy in COVID-19?.Indian J Anaesth 2020;64:835-841


How to cite this URL:
Senniappan K, Jeyabalan S, Rangappa P, Kanchi M. Hyperbaric oxygen therapy: Can it be a novel supportive therapy in COVID-19?. Indian J Anaesth [serial online] 2020 [cited 2020 Oct 23 ];64:835-841
Available from: https://www.ijaweb.org/article.asp?issn=0019-5049;year=2020;volume=64;issue=10;spage=835;epage=841;aulast=Senniappan;type=0