Indian Journal of Anaesthesia

CLINICAL INVESTIGATION
Year
: 2007  |  Volume : 51  |  Issue : 5  |  Page : 401-

Comparison of Bispectral Index Values Produced by Isoflurane and Halothane at Equal End-tidal MAC Concentrations


Neerja Bharti1, Jagan Devrajan2 
1 MD, Assistant Professor, PGIMER, Chandigarh, India
2 MD, Senior Resident, AIIMS, New Delhi, India

Correspondence Address:
Neerja Bharti
Assistant Professor, Department of Anaesthesia & Intensive Care, PGIMER, Chandigarh-160012
India

The bispectral index (BIS) has been validated as a measure of hypnotic effect for various anaesthetic agents. There are limited data correlating the BIS with minimum alveolar concentration (MAC) of different volatile anaesthetics. We compared the BIS values using halothane and isoflurane at equal end-tidal MAC multiples. Forty adult patients of ASAI-II undergoing elective abdominal surgeries were randomly assigned into two groups. After a standardized induction, anaesthesia was maintained with either halothane (Group H) or isoflurane (Group I) in combination with nitrous oxide 66% in oxygen and fentanyl.BIS values were measured before induction, during anaesthesia at 0.5 MAC, 1 MAC, 1.5 MAC concentration of the volatile anaesthetics and then at awakening of the patient. BIS measurements were made after meeting steady state concentrations of volatile anaesthetic agents. BIS values at 0.5 MAC, 1.0 MAC and 1.5 MAC for patients receiving halothane exceeded those for patients receiving isoflurane. BIS value at awakening did not differ between the halothane and isoflurane groups. We concluded that at equal MAC concentrations of halothane and isoflurane BIS values were significantly lower with isoflurane.


How to cite this article:
Bharti N, Devrajan J. Comparison of Bispectral Index Values Produced by Isoflurane and Halothane at Equal End-tidal MAC Concentrations.Indian J Anaesth 2007;51:401-401


How to cite this URL:
Bharti N, Devrajan J. Comparison of Bispectral Index Values Produced by Isoflurane and Halothane at Equal End-tidal MAC Concentrations. Indian J Anaesth [serial online] 2007 [cited 2021 Apr 12 ];51:401-401
Available from: https://www.ijaweb.org/article.asp?issn=0019-5049;year=2007;volume=51;issue=5;spage=401;epage=401;aulast=Bharti;type=0