• Users Online: 8524
  • Print this page
  • Email this page
Year : 2015  |  Volume : 59  |  Issue : 4  |  Page : 216-221

Effect of positive airway pressure during pre-oxygenation and induction of anaesthesia upon safe duration of apnoea

1 Department of Anaesthesiology, Kasturba Medical College, Manipal, Karnataka, India
2 Department of Anaesthesiology, MES Medical College and Hospital, Perinthalmanna, Malappuram, Kerala, India

Correspondence Address:
Dr. Melveetil S Sreejit
Department of Anaesthesiology, MES Medical College and Hospital, Perinthalmanna, Palachode PO, Malappuram - 679 338, Kerala
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0019-5049.154998

Rights and Permissions

Background and Aims: Induction of general anaesthesia per se as also the use of 100% oxygen during induction of anaesthesia, results in the development of atelectasis in dependent lung regions within minutes of anaesthetic induction. We aimed to assess the effect of application of a continuous positive airway pressure (CPAP) of 5 cm H 2 O during pre-oxygenation and induction of anaesthesia on the period of apnoea before the occurrence of clinically significant desaturation. Methods: In this prospective, randomised, and double-blind study, 40 patients posted for elective surgery were enrolled. Duration of apnoea was measured as the time from the administration of succinylcholine hydrochloride to the time when oxygen saturation fell to 93%. Student's t-test was used for comparing the duration of apnoea. Results: The safe duration of apnoea was found to be significantly longer in patients receiving CPAP of 5 cm H 2 O (Group P; n = 16) compared to the group receiving no CPAP (Group Z; n = 20), that is, 496.56 ± 71.68 s versus 273.00 ± 69.31 s (P < 0.001). Conclusion: The application of CPAP of 5 cm H 2 O using a Mapleson "A" circuit with a fixed positive end-expiratory pressure device during 5 min of pre-oxygenation with 100% oxygen prior to the induction of anaesthesia provides a clearly longer duration of apnoea before clinically significant arterial desaturation occurs.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded1178    
    Comments [Add]    
    Cited by others 3    

Recommend this journal